Hyo-Jeong Lee Selected Research

Prostaglandins G

8/2012	Reactive oxygen species-mediated activation of JNK and down-regulation of DAXX are critically involved in penta-O-galloyl-beta-d-glucose-induced apoptosis in chronic myeloid leukemia K562 cells.
8/2011	The genome-wide expression profile of 1,2,3,4,6-penta-O-galloyl-β-D-glucose-treated MDA-MB-231 breast cancer cells: molecular target on cancer metabolism.
6/2011	Oral administration of penta-O-galloyl-β-D-glucose suppresses triple-negative breast cancer xenograft growth and metastasis in strong association with JAK1-STAT3 inhibition.
3/2011	1,2,3,4,6-Penta-O-galloyl-beta-D-glucose reduces renal crystallization and oxidative stress in a hyperoxaluric rat model.
1/2010	Penta-O-galloyl-beta-D-glucose induces G1 arrest and DNA replicative S-phase arrest independently of cyclin-dependent kinase inhibitor 1A, cyclin-dependent kinase inhibitor 1B and P53 in human breast cancer cells and is orally active against triple negative xenograft growth.
1/2010	1,2,3,4,6-Penta-O-galloly-beta-D-glucose suppresses hypoxia-induced accumulation of hypoxia-inducible factor-1α and signaling in LNCaP prostate cancer cells.
9/2008	Penta-1,2,3,4,6-O-galloyl-beta-D-glucose induces p53 and inhibits STAT3 in prostate cancer cells in vitro and suppresses prostate xenograft tumor growth in vivo.

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Hyo-Jeong Lee Research Topics

Disease

54	Neoplasms (Cancer) 06/2022 - 01/2005
26	Prostatic Neoplasms (Prostate Cancer) 06/2022 - 01/2006
12	Hypoxia (Hypoxemia) 06/2022 - 12/2006
9	Breast Neoplasms (Breast Cancer) 03/2019 - 11/2009
9	Neoplasm Metastasis (Metastasis) 01/2017 - 01/2005
8	Deafness (Deaf Mutism) 01/2021 - 11/2007
7	Body Weight (Weight, Body) 01/2022 - 05/2009
7	Carcinogenesis 06/2014 - 03/2007
6	Obesity 06/2022 - 01/2011
5	Inflammation (Inflammations) 01/2022 - 01/2011
5	Colonic Neoplasms (Colon Cancer) 12/2013 - 03/2009
4	Colorectal Neoplasms (Colorectal Cancer) 01/2020 - 01/2013
4	Leukemia 08/2012 - 10/2004
4	Fibrosarcoma 01/2011 - 07/2009
4	Lewis Lung Carcinoma 10/2009 - 12/2006
3	Infections 01/2022 - 11/2010
3	Asthma (Bronchial Asthma) 10/2020 - 10/2011
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2017 - 05/2015
3	Thrombosis (Thrombus) 12/2015 - 12/2009
3	Lung Neoplasms (Lung Cancer) 05/2015 - 11/2008
3	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2013 - 03/2009
3	Atherosclerosis 12/2011 - 04/2009
3	Carcinoma (Carcinomatosis) 01/2011 - 07/2009
3	Hyperplasia 11/2010 - 10/2009
3	Vascular System Injuries 12/2009 - 04/2009
2	Wounds and Injuries (Trauma) 06/2022 - 07/2015
2	Hearing Loss (Hearing Impairment) 01/2022 - 04/2012
2	Thromboembolism 01/2018 - 08/2015
2	Otitis Media 12/2017 - 08/2012
2	Edema (Dropsy) 03/2016 - 04/2012
2	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2013 - 08/2012
2	Arthritis (Polyarthritis) 04/2012 - 03/2009
2	Multiple Myeloma 01/2012 - 06/2011

Drug/Important Bio-Agent (IBA)

13	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 06/2022 - 12/2006
10	Proteins (Proteins, Gene)FDA Link 01/2018 - 01/2005
8	LipidsIBA 11/2021 - 11/2010
7	Androgen Receptors (Androgen Receptor)IBA 09/2020 - 01/2006
7	Ethanol (Ethyl Alcohol)IBA 03/2019 - 01/2006
7	Prostaglandins GIBA 08/2012 - 09/2008
6	AntioxidantsIBA 06/2022 - 07/2009
5	Biological ProductsIBA 06/2022 - 08/2011
5	EnzymesIBA 07/2021 - 01/2010
5	Transcription Factors (Transcription Factor)IBA 02/2017 - 01/2010
4	Small Interfering RNA (siRNA)IBA 09/2020 - 01/2011
4	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 05/2008
4	Triglycerides (Triacylglycerol)IBA 08/2018 - 12/2011
4	sphingosine kinaseIBA 02/2017 - 08/2011
4	Caspase 3 (Caspase-3)IBA 05/2013 - 10/2004
4	CaspasesIBA 05/2013 - 11/2008
4	Messenger RNA (mRNA)IBA 10/2011 - 01/2010
4	AndrogensIBA 01/2011 - 01/2006
4	decursinIBA 12/2010 - 01/2006
4	methylselenic acidIBA 05/2010 - 01/2008
3	PhytochemicalsIBA 06/2022 - 01/2011
3	CholesterolIBA 12/2020 - 01/2013
3	Phosphotransferases (Kinase)IBA 01/2020 - 06/2011
3	AMP-Activated Protein KinasesIBA 01/2020 - 01/2013
3	MelatoninIBA 01/2019 - 08/2011
3	RNA (Ribonucleic Acid)IBA 01/2019 - 11/2010
3	rho-Associated KinasesIBA 01/2017 - 05/2015
3	OsteopontinIBA 01/2017 - 05/2015
3	Actin Depolymerizing Factors (Cofilins)IBA 01/2017 - 05/2015
3	pentagalloylglucoseIBA 08/2012 - 09/2008
3	PENTAIBA 08/2012 - 01/2010
3	p38 Mitogen-Activated Protein KinasesIBA 02/2011 - 01/2010
3	Cisplatin (Platino)FDA LinkGeneric 01/2010 - 03/2009
3	DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA 05/2009 - 10/2004
2	Blood Alcohol ContentIBA 01/2022 - 01/2021
2	Silver Sulfadiazine (SSD)FDA LinkGeneric 01/2021 - 12/2020
2	Coffee FDA Link 10/2020 - 06/2011
2	Prostate-Specific Antigen (Semenogelase)IBA 09/2020 - 07/2009
2	Biomarkers (Surrogate Marker)IBA 04/2020 - 12/2006
2	cadherin 5IBA 01/2020 - 03/2019
2	S-Phase Kinase-Associated Proteins (Skp1 Protein)IBA 03/2019 - 08/2012
2	Caspase 9IBA 03/2019 - 10/2004
2	PuromycinIBA 01/2019 - 01/2013
2	transcription factor UBFIBA 01/2019 - 01/2013
2	Methanol (Carbinol)IBA 05/2018 - 05/2009
2	lambertianic acidIBA 07/2016 - 02/2016
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 03/2016 - 01/2013
2	LDL CholesterolIBA 02/2016 - 01/2013
2	Glycogen Synthase (Synthase I)IBA 01/2016 - 06/2014
2	Therapeutic UsesIBA 01/2015 - 05/2009
2	ResveratrolIBA 02/2014 - 01/2011
2	Nitric Oxide Synthase (NO Synthase)IBA 01/2013 - 07/2009
2	beta-d-glucoseIBA 08/2012 - 01/2010
2	tanshinoneIBA 05/2012 - 01/2010
2	Matrix Metalloproteinases (MMPs)IBA 04/2012 - 07/2009
2	Antineoplastic Agents (Antineoplastics)IBA 08/2011 - 04/2009
2	Paclitaxel (Taxol)FDA LinkGeneric 08/2011 - 11/2008
2	ginsenoside M1IBA 06/2011 - 01/2010
2	SaponinsIBA 06/2011 - 01/2010
2	SurvivinIBA 02/2011 - 12/2010

Therapy/Procedure

8	Therapeutics 01/2022 - 09/2008
6	Chemoprevention 05/2009 - 01/2006
5	Traditional Medicine (Folk Remedies) 01/2022 - 11/2008
5	Cochlear Implants (Cochlear Implant) 12/2020 - 04/2012
3	Oral Administration 06/2012 - 01/2010
2	Mastoidectomy 01/2022 - 12/2017
2	Drug Therapy (Chemotherapy) 05/2018 - 08/2011